Hydroquinone Creams

What is Hydroquinone?

Hydroquinone is a natural product and one of the most effective and at the same time one of the most controversial means against pigment spots. It occurs naturally in coffee, tea, beer and wine. Hydroquinone has been successfully used for decades by dermatologists to treat pigment spots and has been well researched.

The two most important Hydroquinone Creams

Here you can find further information about the two high-dose Hydrochinon creams, which are only available on prescription:

Pigmanorm Widmer Cream (5% hydroquinone)

Obagi Nu Derm System (4% hydroquinone)

How does Hydroquinone work?

Hydroquinone inhibits the transformation of tyrosine in the skin pigment melanin, of which the pigment spots consist. Hydroquinone isn’t a bleaching agent, which means that existing pigment spots can’t be removed, only the formation of new pigment spots can be prevented.

Why do existing pigment spots become lighter?

Source: Deutsche Apothekerzeitung

The melanocytes (pigment cells) lie in the basal layer of the epidermis and release melanin to the surrounding cells.

The pigment cells, also called melanocytes, supply the surrounding skin cells with melanin by continuously releasing melanin in membrane-enveloped melanosomes to the other skin cells. Hydroquinone intervenes in this cycle and reduces the production of further melanosomes. Since the already existing melanosomes (pigment spots) in the skin die after about 4 weeks and have to be continuously replaced by new melanosomes, the pigment spots fade with time, because the production of melanosomes was reduced by the hydroquinone cream. This is a slow process that makes the complexion more even, but already after a few weeks the first results are visible.


Where do I buy Hydroquinone Creams? 🛒

In Germany, the USA and Asia hydroquinone is approved in cosmetic creams in concentrations of 0.5 to 2%. Higher concentrations above 2% are prescription only.

👉Hydroquinone Serum: (AdmireMySkin, US-Shop) 2% Hydrochinon Serum – Melasma- Behandlung & Dark Spot Corrector

The following products can be ordered from Amazon.com and shipped overseas.
👉 Porcelana Cream: (Amazon.com) Porcelana Skin Lightening Day Cream and Fade Dark Spots Treatment, 3 Ounce Contains 2% hydroquinone

👉Porcelain Serum: (Amazon.com) Procelain Skin Whitening Serum Hydroquinone Kojic Acid Glycolic Acid Vitamin C Licorice Mulberry Extract for Melasma This serum contains hydroquinone as well as kojic acid and vitamin C as active ingredients. .

Which Hydroquinone Creams are only available on Prescription?

Creams with high hydroquinone concentration:

Pigmanorm Cream Widmer Contains 5% hydroquinone and is only available on prescription.

Obagi Nu-Derm: This cream contains 4% hydroquinone and must be prescribed by a doctor.


Application Plan – Hydroquinone Cream

#1: Increase the application slowly. Often it’s better to start with one application every three days, if the skin tolerates it well, increase to every other day. Finally, the cream can be used every day. If irritation occurs, reduce it again, as it’s better to avoid irritating the skin too much.
#2: Apply in the evening as this is the best time for treatment.
#3: In addition, use a good moisturizer, because the hydroquinone cream dries the skin a little bit.
#4: Use a good sun cream during the day, as the treatment makes the skin more sensitive to the sun, it must be well protected from the sun.


What Side Effects has Hydroquinone?

Rare cases of ochronosis have been described. The ochronosis is the medical term for the darkening of skin areas. However, these people have used very high doses (over 5%) of hydroquinone-containing creams for many years and have often used additional whitening products, which is not recommended by any doctor.

Is Hydroquinone Carcinogenic?

Hydroquinone is suspected of being carcinogenic, but whether it’s remains to be clarified. Animal experiments with mice have shown that it can be carcinogenic in high doses. In other studies the carcinogenic effect was again refuted (abstract). The possibly carcinogenic effect has discouraged me from using a hydroquinone containing cream as a remedy against my pigment spots, but certainly hydroquinone is one of the strongest active ingredients on the market against pigment spots and has been used for decades.

Sources:
Hydroquinone with Pigment Spots Dr. JETSKE ULTEE Hydroquinone- Wikipedia
Melanocytes – Wikipedia