Vitamin B12: Cobalamin

Cobalamin (vitamin B12): Cobalamin is found mainly in animal products such as eggs, meat, milk and in some algae such as chlorella. During pregnancy, vegetarians can very quickly develop a vitamin B12 deficiency, which is why it’s also recommended to take vitamin B12 during pregnancy as a dietary supplement

A vitamin B12 deficiency is more frequent than many assume! It’s assumed that 6% of under 60-year-olds have a vitamin B12 deficiency and 20% of over 60-year-olds have a vitamin B12 deficiency. A vitamin B12 deficiency can also occur in people who eat meat. However, the risk for vegans and vegetarians is increased. Vitamin B12 deficiency is more common in developing countries. In Africa, for example, up to 80% of the population is affected by a vitamin B12 deficiency. A vitamin B12 deficiency can manifest itself very differently with a variety of symptoms such as skin changes, anaemia, digestive problems (constipation) and finally neuronal disorders. Almost always, however, skin changes occur as the very first sign, and I’ll go into this further…

Do you want to know what the other vitamin B agents do in our bodies? Then continue here ⚡ Vitamin B

Study: Skin changes and vitamin B12 deficiency – an often forgotten connection

The following study investigated 63 patients with vitamin B12 deficiency: 👉 Cutaneous lesions and vitamin B12 deficiency – An often-forgotten link

The authors of the study point out that in the early stages of vitamin B12 deficiency, often no diagnosis is made. The symptoms of vitamin B12 deficiency are very unspecific. However, skin changes are almost always the first sign. There are very few known cases where other symptoms have occurred before the skin lesions described below.

The 63 patients in the study had the following skin lesions: 41% skin and mucous membrane changes, 31% glossitis (inflammation of the tongue), 19% hyperpigmentation of the skin, 9% hair changes, 8% inflammation of the corner of the mouth, 3% vitiligo (white spot disease)

Conclusion of the study

A patient presenting with cutaneous lesions alone should make us highly suspicious of the possibility of vitamin B12 deficiency. We should be more aware that cutaneous lesions not responding to conventional therapy could very likely be an indication of vitamin B12 deficiency. These skin manifestations respond quickly to vitamin B12 therapy. Early treatment with vitamin B12 will prevent the serious complications of vitamin B12 deficiency.
Malabsorption is the most common cause of vitamin B12 deficiency. Initial replacement is usually through intramuscular injections. Those with normal absorption can be maintained on oral replacement.

Source: Cutaneous lesions and vitamin B12 deficiency An often-forgotten link

Vitamin B12 & Melasma

Expectant mothers have a 50 to 100% increased need for nutrients and minerals compared to non-pregnant mothers, as the growing baby is also supplied. During pregnancy, doctors recommend taking additional folic acid, as this B vitamin is very important for the healthy development of the baby. Due to the increased nutrient requirement during pregnancy, a lack of vitamin B12 and folic acid can easily occur, especially in vegetarians and vegans. Pregnant women and persons over 60 years of age are at risk of vitamin B12 deficiency. As you can see, it’s quite imaginable that a pregnancy results in a vitamin B12 deficiency. Especially in people who have a worse absorption of vitamin B12 …

The interplay of vitamin B 12 and folic acid

The interaction of vitamin B12 with folic acid (vitamin B9) is also interesting. Only vitamin B12 can convert folic acid into the body’s available form of folate. What many don’t know: A vitamin B12 deficiency leads to an indirect, functional folic acid deficiency. The two vitamins are like siblings and can only work together.


Where can I buy vitamin B12? 🛒

👉 VegLife B-12 Plus Folic Acid Vegan Lozenge, 1000 mcg, Orange, 50 Count (3 Pack) High dosed with 1000mcg of vitamin B12 and 400 mcg of folic acid. Can help with pigment spots, but also with symptoms such as fatigue and lack of energy.


Do you want to know more about vitamin B12?

⚡ Here’s to my summary of Dr. Desai’s article in the Dermatology Times: New treatments and approaches in melasma: Tranexamic Acid and Vitamin B12

This study on vitamin B12 as well is interesting
👉 Reversible Facial Hyperpigmentation Associated With Vitamin B12 Deficiency.

Sources:
Cutaneous lesions and vitamin B12 deficiency An often-forgotten link
Cobalamine – Wikipedia
Darum sind das Vitamin B12 und die Folsäure beste Freunde